Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2504383..2504567 Replicon chromosome
Accession NZ_LS483317
Organism Staphylococcus aureus strain NCTC5663

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DQL75_RS12930 Protein ID WP_000482647.1
Coordinates 2504460..2504567 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2504383..2504443 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL75_RS12905 2499836..2500003 - 168 WP_001789205.1 hypothetical protein -
DQL75_RS12915 2500234..2501967 - 1734 WP_111762661.1 ABC transporter ATP-binding protein/permease -
DQL75_RS12920 2501992..2503756 - 1765 Protein_2395 ABC transporter ATP-binding protein -
- 2504383..2504443 + 61 - - Antitoxin
DQL75_RS12930 2504460..2504567 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL75_RS12935 2504701..2505087 - 387 WP_000779353.1 flippase GtxA -
DQL75_RS12940 2505355..2506497 + 1143 WP_001176863.1 glycerate kinase -
DQL75_RS12945 2506557..2507216 + 660 WP_000831304.1 hypothetical protein -
DQL75_RS12950 2507399..2508610 + 1212 WP_001191924.1 multidrug effflux MFS transporter -
DQL75_RS12955 2508733..2509206 - 474 WP_111762662.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T292341 WP_000482647.1 NZ_LS483317:c2504567-2504460 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292341 NZ_LS483317:2504383-2504443 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References