Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2213961..2214224 Replicon chromosome
Accession NZ_LS483317
Organism Staphylococcus aureus strain NCTC5663

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DQL75_RS11380 Protein ID WP_001802298.1
Coordinates 2214120..2214224 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2213961..2214125 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL75_RS11360 2210077..2210742 - 666 WP_001024100.1 SDR family oxidoreductase -
DQL75_RS11365 2210894..2211214 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL75_RS11370 2211216..2212196 + 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
DQL75_RS11375 2212462..2213553 + 1092 WP_111762538.1 transcriptional regulator -
- 2213961..2214125 + 165 - - Antitoxin
DQL75_RS11380 2214120..2214224 - 105 WP_001802298.1 hypothetical protein Toxin
DQL75_RS11385 2214385..2214885 - 501 Protein_2110 recombinase family protein -
DQL75_RS11390 2214928..2216064 - 1137 WP_111762539.1 SAP domain-containing protein -
DQL75_RS11395 2217107..2217964 - 858 WP_111762540.1 Cof-type HAD-IIB family hydrolase -
DQL75_RS11400 2218031..2218813 - 783 WP_111762541.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T292338 WP_001802298.1 NZ_LS483317:c2214224-2214120 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT292338 NZ_LS483317:2213961-2214125 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References