292327

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2546652..2546836 Replicon chromosome
Accession NZ_LS483316
Organism Staphylococcus aureus strain NCTC13395

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag DQL73_RS13445 Protein ID WP_000482650.1
Coordinates 2546729..2546836 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2546652..2546712 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL73_RS13420 2542182..2542349 - 168 WP_001790576.1 hypothetical protein -
DQL73_RS13430 2542580..2544313 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DQL73_RS13435 2544338..2546101 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2546652..2546712 + 61 - - Antitoxin
DQL73_RS13445 2546729..2546836 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL73_RS13450 2546970..2547356 - 387 WP_000779358.1 flippase GtxA -
DQL73_RS13455 2547624..2548766 + 1143 WP_001176863.1 glycerate kinase -
DQL73_RS13460 2548826..2549485 + 660 WP_000831298.1 membrane protein -
DQL73_RS13465 2549667..2550878 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DQL73_RS13470 2551001..2551474 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T292327 WP_000482650.1 NZ_LS483316:c2546836-2546729 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292327 NZ_LS483316:2546652-2546712 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References