292325

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2256348..2256565 Replicon chromosome
Accession NZ_LS483316
Organism Staphylococcus aureus strain NCTC13395

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DQL73_RS11860 Protein ID WP_001802298.1
Coordinates 2256461..2256565 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2256348..2256403 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL73_RS11840 2252485..2253150 - 666 WP_045177733.1 SDR family oxidoreductase -
DQL73_RS11845 2253302..2253622 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL73_RS11850 2253624..2254604 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
DQL73_RS11855 2254870..2255961 + 1092 WP_000495671.1 lytic regulatory protein -
- 2256348..2256403 + 56 - - Antitoxin
DQL73_RS11860 2256461..2256565 - 105 WP_001802298.1 hypothetical protein Toxin
DQL73_RS15070 2256726..2257209 - 484 Protein_2183 recombinase family protein -
DQL73_RS11870 2257252..2258388 - 1137 WP_000115564.1 SAP domain-containing protein -
DQL73_RS11875 2258677..2258769 + 93 WP_001790138.1 hypothetical protein -
DQL73_RS11880 2259474..2260331 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
DQL73_RS11885 2260399..2261181 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T292325 WP_001802298.1 NZ_LS483316:c2256565-2256461 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT292325 NZ_LS483316:2256348-2256403 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References