Detailed information of TA system TA292319

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF3/-
• Location: 2078958..2079257
• Replicon: chromosome
• Accession: NZ_LS483316
• Organism: Staphylococcus aureus strain NCTC13395

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: DQL73_RS10810
• Protein ID: WP_072353918.1
• Coordinates: 2079081..2079257 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2078958..2079013 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQL73_RS10750	2074517..2074696	+	180	WP_000669791.1	hypothetical protein	-
DQL73_RS10760	2075007..2075267	+	261	WP_001791826.1	hypothetical protein	-
DQL73_RS10765	2075320..2075670	-	351	WP_000702263.1	complement inhibitor SCIN-A	-
DQL73_RS10770	2076180..2076515	-	336	Protein_1979	SH3 domain-containing protein	-
DQL73_RS10790	2077166..2077657	-	492	WP_000920038.1	staphylokinase	-
DQL73_RS10795	2077848..2078603	-	756	WP_000861038.1	CHAP domain-containing protein	-
DQL73_RS10800	2078615..2078869	-	255	WP_000611512.1	phage holin	-
DQL73_RS10805	2078921..2079028	+	108	WP_001791821.1	hypothetical protein	-
-	2078950..2079089	+	140	NuclAT_0	-	-
-	2078950..2079089	+	140	NuclAT_0	-	-
-	2078950..2079089	+	140	NuclAT_0	-	-
-	2078950..2079089	+	140	NuclAT_0	-	-
-	2078958..2079013	+	56	-	-	Antitoxin
DQL73_RS10810	2079081..2079257	-	177	WP_072353918.1	putative holin-like toxin	Toxin
DQL73_RS10815	2079400..2079774	-	375	WP_111761281.1	hypothetical protein	-
DQL73_RS10820	2079830..2080117	-	288	WP_001262621.1	hypothetical protein	-
DQL73_RS10825	2080163..2080315	-	153	WP_001000058.1	hypothetical protein	-
DQL73_RS10830	2080308..2084090	-	3783	WP_031901052.1	phage minor structural protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / sak / hlb / groEL	2075320..2131305	55985

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6810.43 Da
• Isoelectric Point: 9.9479

>T292319 WP_072353918.1 NZ_LS483316:c2079257-2079081 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 56 bp

>AT292319 NZ_LS483316:2078958-2079013 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin