Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2537444..2537628 Replicon chromosome
Accession NZ_LS483311
Organism Staphylococcus aureus strain NCTC6136

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DQL83_RS13460 Protein ID WP_000482647.1
Coordinates 2537521..2537628 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2537444..2537504 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL83_RS13435 2532974..2533141 - 168 WP_001790576.1 hypothetical protein -
DQL83_RS13445 2533372..2535105 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DQL83_RS13450 2535130..2536893 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 2537444..2537504 + 61 - - Antitoxin
DQL83_RS13460 2537521..2537628 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL83_RS13465 2537762..2538148 - 387 WP_000779360.1 flippase GtxA -
DQL83_RS13470 2538406..2539548 + 1143 WP_001176863.1 glycerate kinase -
DQL83_RS13475 2539608..2540267 + 660 WP_000831298.1 membrane protein -
DQL83_RS13480 2540449..2541660 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DQL83_RS13485 2541783..2542256 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T292300 WP_000482647.1 NZ_LS483311:c2537628-2537521 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292300 NZ_LS483311:2537444-2537504 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References