Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2252715..2252931 Replicon chromosome
Accession NZ_LS483311
Organism Staphylococcus aureus strain NCTC6136

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DQL83_RS11910 Protein ID WP_001802298.1
Coordinates 2252827..2252931 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2252715..2252770 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL83_RS11890 2248909..2249574 - 666 WP_001024095.1 SDR family oxidoreductase -
DQL83_RS11895 2249726..2250046 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL83_RS11900 2250048..2251028 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
DQL83_RS11905 2251294..2252385 + 1092 WP_000495681.1 hypothetical protein -
- 2252715..2252770 + 56 - - Antitoxin
DQL83_RS11910 2252827..2252931 - 105 WP_001802298.1 hypothetical protein Toxin
DQL83_RS15115 2253448..2253618 + 171 WP_001792292.1 transposase -
DQL83_RS11920 2253611..2253769 + 159 WP_001792784.1 hypothetical protein -
DQL83_RS11930 2254427..2255284 - 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
DQL83_RS11935 2255352..2256134 - 783 WP_000908180.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T292297 WP_001802298.1 NZ_LS483311:c2252931-2252827 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT292297 NZ_LS483311:2252715-2252770 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References