Detailed information of TA system TA029228

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1834743..1834923
• Replicon: chromosome
• Accession: NC_020568
• Organism: Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAI8T7_RS14805
• Protein ID: WP_001801861.1
• Coordinates: 1834743..1834838 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1834866..1834923 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAI8T7_RS08865	1829906..1830556	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAI8T7_RS08870	1830637..1831632	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAI8T7_RS08875	1831707..1832333	+	627	WP_000669024.1	hypothetical protein	-
SAI8T7_RS08880	1832374..1832715	+	342	WP_000627540.1	DUF3969 family protein	-
SAI8T7_RS08885	1832816..1833388	+	573	WP_000414216.1	hypothetical protein	-
SAI8T7_RS14450	1833586..1834598	-	1013	Protein_1703	IS3 family transposase	-
SAI8T7_RS14805	1834743..1834838	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1834866..1834923	-	58	-	-	Antitoxin
SAI8T7_RS08905	1834961..1835062	+	102	WP_001792025.1	hypothetical protein	-
SAI8T7_RS14810	1835040..1835201	-	162	Protein_1706	transposase	-
SAI8T7_RS08910	1835192..1835686	-	495	Protein_1707	transposase	-
SAI8T7_RS08915	1836138..1837366	-	1229	Protein_1708	restriction endonuclease subunit S	-
SAI8T7_RS08920	1837359..1838915	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
SAI8T7_RS08925	1839079..1839213	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1810601..1861745	51144

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29228 WP_001801861.1 NC_020568:1834743-1834838 [Staphylococcus aureus subsp. aureus ST228]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29228 NC_020568:1834743-1834838 [Staphylococcus aureus subsp. aureus ST228]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29228 NC_020568:c1834923-1834866 [Staphylococcus aureus subsp. aureus ST228]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin