Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2316989..2317206 Replicon chromosome
Accession NZ_LS483309
Organism Staphylococcus aureus strain NCTC9944

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DQL96_RS12225 Protein ID WP_001802298.1
Coordinates 2317102..2317206 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2316989..2317044 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL96_RS12205 2313126..2313791 - 666 WP_001024094.1 SDR family oxidoreductase -
DQL96_RS12210 2313943..2314263 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL96_RS12215 2314265..2315245 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
DQL96_RS12220 2315511..2316602 + 1092 WP_000495671.1 lytic regulatory protein -
- 2316989..2317044 + 56 - - Antitoxin
DQL96_RS12225 2317102..2317206 - 105 WP_001802298.1 hypothetical protein Toxin
DQL96_RS15560 2317367..2317850 - 484 Protein_2261 recombinase family protein -
DQL96_RS12235 2317893..2319029 - 1137 WP_000115564.1 SAP domain-containing protein -
DQL96_RS12240 2319318..2319410 + 93 WP_001790138.1 hypothetical protein -
DQL96_RS12245 2320115..2320972 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
DQL96_RS12250 2321040..2321822 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T292271 WP_001802298.1 NZ_LS483309:c2317206-2317102 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT292271 NZ_LS483309:2316989-2317044 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References