292256

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2449019..2449203 Replicon chromosome
Accession NZ_LS483308
Organism Staphylococcus aureus strain NCTC13137

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DQL85_RS12755 Protein ID WP_000482647.1
Coordinates 2449096..2449203 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2449019..2449079 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL85_RS12730 2444470..2444637 - 168 WP_031860495.1 hypothetical protein -
DQL85_RS12740 2444868..2446601 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DQL85_RS12745 2446626..2448389 - 1764 WP_006191000.1 ABC transporter ATP-binding protein/permease -
- 2449019..2449079 + 61 - - Antitoxin
DQL85_RS12755 2449096..2449203 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL85_RS12760 2449337..2449723 - 387 WP_000779360.1 flippase GtxA -
DQL85_RS12765 2449991..2451133 + 1143 WP_001176863.1 glycerate kinase -
DQL85_RS12770 2451193..2451852 + 660 WP_000831298.1 membrane protein -
DQL85_RS12775 2452034..2453245 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DQL85_RS12780 2453368..2453841 - 474 WP_006191009.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T292256 WP_000482647.1 NZ_LS483308:c2449203-2449096 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292256 NZ_LS483308:2449019-2449079 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References