Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2164727..2164943 Replicon chromosome
Accession NZ_LS483308
Organism Staphylococcus aureus strain NCTC13137

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag DQL85_RS11215 Protein ID WP_075583739.1
Coordinates 2164839..2164943 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2164727..2164782 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL85_RS11195 2160861..2161526 - 666 WP_001024095.1 SDR family oxidoreductase -
DQL85_RS11200 2161678..2161998 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL85_RS11205 2162000..2162977 + 978 WP_006190804.1 CDF family zinc efflux transporter CzrB -
DQL85_RS11210 2163243..2164334 + 1092 WP_000495682.1 hypothetical protein -
- 2164727..2164782 + 56 - - Antitoxin
DQL85_RS11215 2164839..2164943 - 105 WP_075583739.1 hypothetical protein Toxin
DQL85_RS11220 2165041..2165181 - 141 Protein_2072 helix-turn-helix domain-containing protein -
DQL85_RS11230 2165620..2165778 + 159 WP_024928151.1 hypothetical protein -
DQL85_RS11235 2166226..2166318 + 93 WP_000142674.1 hypothetical protein -
DQL85_RS11240 2166439..2167296 - 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
DQL85_RS11245 2167364..2168146 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T292253 WP_075583739.1 NZ_LS483308:c2164943-2164839 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT292253 NZ_LS483308:2164727-2164782 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References