Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 118019..118532 Replicon chromosome
Accession NZ_LS483305
Organism Mammaliicoccus sciuri strain NCTC12103

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DQL71_RS00505 Protein ID WP_048540372.1
Coordinates 118266..118532 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DQL71_RS00500 Protein ID WP_048540371.1
Coordinates 118019..118273 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL71_RS00475 113232..114155 + 924 WP_048540366.1 NAD-dependent epimerase/dehydratase family protein -
DQL71_RS00480 114157..114852 + 696 WP_048540367.1 type 1 glutamine amidotransferase domain-containing protein -
DQL71_RS00485 114925..116250 - 1326 WP_048540368.1 MFS transporter -
DQL71_RS00490 116405..116830 + 426 WP_048540369.1 MerR family transcriptional regulator -
DQL71_RS00495 116892..117740 + 849 WP_048540370.1 aldo/keto reductase -
DQL71_RS00500 118019..118273 + 255 WP_048540371.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DQL71_RS00505 118266..118532 + 267 WP_048540372.1 Txe/YoeB family addiction module toxin Toxin
DQL71_RS00510 118691..119029 + 339 WP_048540373.1 hypothetical protein -
DQL71_RS00515 119062..119952 - 891 WP_048540374.1 ABC transporter permease subunit -
DQL71_RS00520 119949..120803 - 855 WP_048540375.1 ABC transporter permease subunit -
DQL71_RS00525 120966..121445 - 480 WP_048540376.1 GNAT family N-acetyltransferase -
DQL71_RS00530 121595..121954 - 360 WP_048540377.1 hypothetical protein -
DQL71_RS00535 122002..122568 - 567 WP_048540378.1 histidine phosphatase family protein -
DQL71_RS14035 122913..123161 + 249 WP_048540379.1 SDR family oxidoreductase -
DQL71_RS14040 123197..123442 + 246 WP_048540380.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10467.10 Da        Isoelectric Point: 9.6422

>T292240 WP_048540372.1 NZ_LS483305:118266-118532 [Mammaliicoccus sciuri]
MSKRNITFTPTAFEDYEYWLAQDKKLLKKINSLIKSIQRDGQLEGEGKPEPLKGNLQGYCSRRINHEHRLVYMVKENHII
IIGCRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9518.44 Da        Isoelectric Point: 4.2086

>AT292240 WP_048540371.1 NZ_LS483305:118019-118273 [Mammaliicoccus sciuri]
MTVISYSNARKNFRKLIDKVNNDSDTVTITTNESNAVLMGEDDYNSIMETLYLQQSPANAKHLAKSIEEAERNNTVEVDI
DSYE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References