Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2446438..2446622 Replicon chromosome
Accession NZ_LS483302
Organism Staphylococcus aureus strain NCTC8726

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DQL80_RS12600 Protein ID WP_000482647.1
Coordinates 2446515..2446622 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2446438..2446498 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL80_RS12575 2441953..2442120 - 168 WP_111680597.1 hypothetical protein -
DQL80_RS12585 2442346..2444079 - 1734 WP_000488491.1 ABC transporter ATP-binding protein/permease -
DQL80_RS12590 2444128..2445867 - 1740 WP_001064832.1 ABC transporter ATP-binding protein/permease -
- 2446438..2446498 + 61 - - Antitoxin
DQL80_RS12600 2446515..2446622 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL80_RS12605 2446756..2447142 - 387 WP_000779354.1 flippase GtxA -
DQL80_RS12610 2447410..2448552 + 1143 WP_111680598.1 glycerate kinase -
DQL80_RS12615 2448612..2449271 + 660 WP_111680599.1 hypothetical protein -
DQL80_RS12620 2449451..2450662 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
DQL80_RS12625 2450785..2451258 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T292222 WP_000482647.1 NZ_LS483302:c2446622-2446515 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292222 NZ_LS483302:2446438-2446498 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References