Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2319719..2319998 Replicon chromosome
Accession NZ_LS483301
Organism Staphylococcus aureus strain NCTC13394

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DQL88_RS12370 Protein ID WP_001802298.1
Coordinates 2319894..2319998 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2319719..2319898 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL88_RS12350 2315918..2316583 - 666 WP_045177733.1 SDR family oxidoreductase -
DQL88_RS12355 2316735..2317055 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL88_RS12360 2317057..2318037 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
DQL88_RS12365 2318303..2319394 + 1092 WP_000495671.1 lytic regulatory protein -
- 2319719..2319898 + 180 - - Antitoxin
DQL88_RS12370 2319894..2319998 - 105 WP_001802298.1 hypothetical protein Toxin
DQL88_RS15640 2320159..2320642 - 484 Protein_2275 recombinase family protein -
DQL88_RS12380 2320685..2321821 - 1137 WP_000115564.1 SAP domain-containing protein -
DQL88_RS12385 2322110..2322202 + 93 WP_001790138.1 hypothetical protein -
DQL88_RS12395 2322655..2323827 + 1173 WP_000195429.1 IS256-like element IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2322655..2323827 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T292209 WP_001802298.1 NZ_LS483301:c2319998-2319894 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT292209 NZ_LS483301:2319719-2319898 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References