Detailed information of TA system TA292202

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1958596..1958778
• Replicon: chromosome
• Accession: NZ_LS483301
• Organism: Staphylococcus aureus strain NCTC13394

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: DQL88_RS10055
• Protein ID: WP_001801861.1
• Coordinates: 1958596..1958691 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1958719..1958778 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQL88_RS10005	1954256..1954882	+	627	WP_000669046.1	hypothetical protein	-
DQL88_RS10010	1954923..1955267	+	345	WP_000627551.1	DUF3969 family protein	-
DQL88_RS10015	1955365..1955916	+	552	WP_000414205.1	hypothetical protein	-
DQL88_RS10020	1956134..1956775	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
DQL88_RS10025	1956889..1957074	-	186	WP_000809857.1	hypothetical protein	-
DQL88_RS10030	1957076..1957252	-	177	WP_000375476.1	hypothetical protein	-
DQL88_RS10035	1957263..1957646	-	384	WP_000070811.1	hypothetical protein	-
DQL88_RS10045	1958250..1958393	-	144	WP_001549059.1	transposase	-
DQL88_RS10055	1958596..1958691	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1958719..1958778	-	60	-	-	Antitoxin
DQL88_RS10060	1958814..1958915	+	102	WP_001791893.1	hypothetical protein	-
DQL88_RS10065	1958893..1959069	-	177	Protein_1886	transposase	-
DQL88_RS10070	1959263..1959640	-	378	WP_001037045.1	DUF1433 domain-containing protein	-
DQL88_RS10075	1960420..1962024	-	1605	WP_000284571.1	IS1182-like element IS1182 family transposase	-
DQL88_RS10080	1962181..1963329	-	1149	Protein_1889	ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / lukD / hlgA	1951695..2031650	79955

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T292202 WP_001801861.1 NZ_LS483301:1958596-1958691 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT292202 NZ_LS483301:c1958778-1958719 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin