Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2434289..2434812 Replicon chromosome
Accession NZ_LS483300
Organism Staphylococcus aureus strain NCTC7485

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DQL62_RS12630 Protein ID WP_001067424.1
Coordinates 2434289..2434555 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DQL62_RS12635 Protein ID WP_000587621.1
Coordinates 2434555..2434812 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL62_RS12610 2429497..2430684 - 1188 WP_045157510.1 MFS transporter -
DQL62_RS12615 2431080..2431856 - 777 WP_000072158.1 iron export ABC transporter permease subunit FetB -
DQL62_RS12620 2431849..2432511 - 663 WP_000923510.1 ATP-binding cassette domain-containing protein -
DQL62_RS12625 2432857..2433933 - 1077 WP_001072887.1 M42 family metallopeptidase -
DQL62_RS12630 2434289..2434555 - 267 WP_001067424.1 Txe/YoeB family addiction module toxin Toxin
DQL62_RS12635 2434555..2434812 - 258 WP_000587621.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DQL62_RS12640 2435171..2435626 + 456 WP_000732077.1 YehR family lipoprotein -
DQL62_RS12645 2435794..2437371 - 1578 WP_045157511.1 FMN-binding glutamate synthase family protein -
DQL62_RS12650 2437565..2438314 + 750 WP_000072450.1 hypothetical protein -
DQL62_RS12655 2438538..2439731 - 1194 WP_000675394.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10725.40 Da        Isoelectric Point: 10.1384

>T292198 WP_001067424.1 NZ_LS483300:c2434555-2434289 [Staphylococcus aureus]
MNNYTVKIKNSAKLDLKKIKHPYLKKSFLEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRIVYTVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9796.79 Da        Isoelectric Point: 4.3304

>AT292198 WP_000587621.1 NZ_LS483300:c2434812-2434555 [Staphylococcus aureus]
MIITSPTEARKHFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKNIQETIYLESTGTMDKVREREKDSSGTTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References