Detailed information of TA system TA292197

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2403062..2403246
• Replicon: chromosome
• Accession: NZ_LS483300
• Organism: Staphylococcus aureus strain NCTC7485

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: DQL62_RS12475
• Protein ID: WP_000482649.1
• Coordinates: 2403139..2403246 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2403062..2403122 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQL62_RS12450	2398656..2398823	-	168	WP_001798790.1	hypothetical protein	-
DQL62_RS12460	2399054..2400786	-	1733	Protein_2291	ABC transporter ATP-binding protein	-
DQL62_RS12465	2400811..2402574	-	1764	Protein_2292	ABC transporter ATP-binding protein	-
-	2403062..2403122	+	61	-	-	Antitoxin
DQL62_RS12475	2403139..2403246	-	108	WP_000482649.1	type I toxin-antitoxin system Fst family toxin	Toxin
DQL62_RS12480	2403381..2403767	-	387	WP_000779353.1	flippase GtxA	-
DQL62_RS12485	2404035..2405177	+	1143	WP_001176861.1	glycerate kinase	-
DQL62_RS12490	2405237..2405896	+	660	WP_000831304.1	hypothetical protein	-
DQL62_RS12495	2406079..2407290	+	1212	WP_001191925.1	multidrug effflux MFS transporter	-
DQL62_RS12500	2407413..2407886	-	474	WP_000456485.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3958.73 Da
• Isoelectric Point: 9.5674

>T292197 WP_000482649.1 NZ_LS483300:c2403246-2403139 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTCNNKKGDK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 61 bp

>AT292197 NZ_LS483300:2403062-2403122 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTATTGCCGTAGTGAGGGGA

Structures

Antitoxin