Detailed information of TA system TA292191

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 976837..977055
• Replicon: chromosome
• Accession: NZ_LS483300
• Organism: Staphylococcus aureus strain NCTC7485

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DQL62_RS04970
• Protein ID: WP_000623369.1
• Coordinates: 976837..976944 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF
Locus tag	-
Coordinates	976939..977055 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQL62_RS04945	973510..974079	-	570	WP_000283455.1	competence protein ComK	-
DQL62_RS04950	974289..974507	+	219	WP_000876826.1	IDEAL domain-containing protein	-
DQL62_RS04955	974588..975574	-	987	WP_000668820.1	lipoate--protein ligase	-
DQL62_RS04960	975773..975949	+	177	WP_000214898.1	YkvS family protein	-
DQL62_RS04965	975964..976566	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DQL62_RS04970	976837..976944	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	976939..977055	-	117	-	-	Antitoxin
DQL62_RS04975	977483..977584	+	102	WP_042852647.1	hypothetical protein	-
DQL62_RS04980	977594..977866	+	273	WP_078062708.1	lactococcin 972 family bacteriocin	-
DQL62_RS04985	977909..979873	+	1965	WP_000870792.1	bacteriocin-associated integral membrane family protein	-
DQL62_RS04990	979876..980199	+	324	WP_000668625.1	YxeA family protein	-
DQL62_RS04995	980196..980834	+	639	WP_042852651.1	ABC transporter ATP-binding protein	-
DQL62_RS05000	980922..981212	-	291	WP_001795266.1	hypothetical protein	-
DQL62_RS05005	981545..981832	+	288	WP_000410749.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T292191 WP_000623369.1 NZ_LS483300:976837-976944 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 117 bp

>AT292191 NZ_LS483300:c977055-976939 [Staphylococcus aureus]
TGTAAAAAGACGACATGCAGGAACATGTCGCCAAATGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACC
ATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin