Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 3757909..3758593 Replicon chromosome
Accession NZ_LS483250
Organism Moritella yayanosii strain DB21MT 5

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag MORIYA_RS17445 Protein ID WP_112717219.1
Coordinates 3758180..3758593 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag MORIYA_RS17440 Protein ID WP_197713400.1
Coordinates 3757909..3758196 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MORIYA_RS17410 3753249..3753698 + 450 WP_112717207.1 hypothetical protein -
MORIYA_RS17415 3753717..3754343 + 627 WP_112717209.1 UbiX family flavin prenyltransferase -
MORIYA_RS17420 3754347..3754985 - 639 WP_112717211.1 TetR/AcrR family transcriptional regulator -
MORIYA_RS17425 3755343..3755876 + 534 WP_112717213.1 hypoxanthine phosphoribosyltransferase -
MORIYA_RS17430 3756143..3757069 + 927 WP_112717215.1 ABC transporter ATP-binding protein -
MORIYA_RS17435 3757066..3757836 + 771 WP_112717217.1 ABC transporter permease -
MORIYA_RS17440 3757909..3758196 + 288 WP_197713400.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
MORIYA_RS17445 3758180..3758593 + 414 WP_112717219.1 type II toxin-antitoxin system YafO family toxin Toxin
MORIYA_RS17450 3758714..3759415 + 702 WP_112717221.1 SAM-dependent methyltransferase -
MORIYA_RS17455 3759513..3760706 - 1194 WP_112717223.1 LPS O-antigen chain length determinant protein WzzB -
MORIYA_RS17460 3761244..3762863 + 1620 WP_112714498.1 IS1634 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(33-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15951.24 Da        Isoelectric Point: 6.6327

>T292135 WP_112717219.1 NZ_LS483250:3758180-3758593 [Moritella yayanosii]
MNLSNNIRIFKSRPLIESLNESELSSLVSDFKLYKLTGQLPDTFGCDVPYDHPNTMPTLKNEDVRHLHLLDEDMKWQVNK
LQFYKTSDTHLVYCQGGVDENCYLLIAVLSPNAHEQARNNQVMFKIAIMAENFRRKF

Download         Length: 414 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10930.52 Da        Isoelectric Point: 4.3030

>AT292135 WP_197713400.1 NZ_LS483250:3757909-3758196 [Moritella yayanosii]
MTIQTIYAEKTVSVTDVRKNPCQYFIEEPVAVLSNNKTAGYMVSKDMFESMLELIDSKLIQAKFRLSKDRLKELAVLNEE
YLLSASDDDLNEFIE

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References