Detailed information of TA system TA029213

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1834880..1835060
• Replicon: chromosome
• Accession: NC_020566
• Organism: Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAI5S5_RS14880
• Protein ID: WP_001801861.1
• Coordinates: 1834880..1834975 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1835003..1835060 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAI5S5_RS08860	1830043..1830693	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAI5S5_RS08865	1830774..1831769	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAI5S5_RS08870	1831844..1832470	+	627	WP_000669024.1	hypothetical protein	-
SAI5S5_RS08875	1832511..1832852	+	342	WP_000627540.1	DUF3969 family protein	-
SAI5S5_RS08880	1832953..1833525	+	573	WP_000414216.1	hypothetical protein	-
SAI5S5_RS14535	1833723..1834735	-	1013	Protein_1702	IS3 family transposase	-
SAI5S5_RS14880	1834880..1834975	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1835003..1835060	-	58	-	-	Antitoxin
SAI5S5_RS08900	1835098..1835199	+	102	WP_001792025.1	hypothetical protein	-
SAI5S5_RS14885	1835177..1835338	-	162	Protein_1705	transposase	-
SAI5S5_RS08905	1835329..1835823	-	495	Protein_1706	transposase	-
SAI5S5_RS08910	1836275..1837503	-	1229	Protein_1707	restriction endonuclease subunit S	-
SAI5S5_RS08915	1837496..1839051	-	1556	Protein_1708	type I restriction-modification system subunit M	-
SAI5S5_RS08920	1839215..1839349	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1810737..1861884	51147

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29213 WP_001801861.1 NC_020566:1834880-1834975 [Staphylococcus aureus subsp. aureus ST228]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29213 NC_020566:1834880-1834975 [Staphylococcus aureus subsp. aureus ST228]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29213 NC_020566:c1835060-1835003 [Staphylococcus aureus subsp. aureus ST228]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin