Detailed information of TA system TA029198

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1834924..1835104
• Replicon: chromosome
• Accession: NC_020564
• Organism: Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAI2T2_RS15985
• Protein ID: WP_001801861.1
• Coordinates: 1834924..1835019 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1835047..1835104 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAI2T2_RS08860	1830087..1830737	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAI2T2_RS08865	1830818..1831813	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAI2T2_RS08870	1831888..1832514	+	627	WP_000669024.1	hypothetical protein	-
SAI2T2_RS08875	1832555..1832896	+	342	WP_000627540.1	DUF3969 family protein	-
SAI2T2_RS08880	1832997..1833569	+	573	WP_000414216.1	hypothetical protein	-
SAI2T2_RS15620	1833767..1834779	-	1013	Protein_1701	IS3 family transposase	-
SAI2T2_RS15985	1834924..1835019	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1835047..1835104	-	58	-	-	Antitoxin
SAI2T2_RS14765	1835142..1835243	+	102	WP_001792025.1	hypothetical protein	-
SAI2T2_RS15990	1835221..1835382	-	162	Protein_1704	transposase	-
SAI2T2_RS08905	1835373..1835867	-	495	Protein_1705	transposase	-
SAI2T2_RS08910	1836319..1837545	-	1227	Protein_1706	restriction endonuclease subunit S	-
SAI2T2_RS08915	1837538..1839094	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
SAI2T2_RS14770	1839258..1839392	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1810785..1861928	51143

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29198 WP_001801861.1 NC_020564:1834924-1835019 [Staphylococcus aureus subsp. aureus ST228]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29198 NC_020564:1834924-1835019 [Staphylococcus aureus subsp. aureus ST228]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29198 NC_020564:c1835104-1835047 [Staphylococcus aureus subsp. aureus ST228]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin