Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2156118..2156334 Replicon chromosome
Accession NC_020537
Organism Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAI7S6_RS14895 Protein ID WP_001802298.1
Coordinates 2156230..2156334 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2156118..2156173 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAI7S6_RS10825 2151677..2152054 - 378 WP_000361059.1 transposase -
SAI7S6_RS10830 2152061..2153953 - 1893 WP_001557544.1 site-specific integrase -
SAI7S6_RS10835 2153950..2155035 - 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
SAI7S6_RS10840 2155153..2155797 + 645 Protein_2044 transcriptional regulator -
- 2156118..2156173 + 56 - - Antitoxin
SAI7S6_RS14895 2156230..2156334 - 105 WP_001802298.1 hypothetical protein Toxin
SAI7S6_RS16045 2156851..2157021 + 171 WP_001792292.1 transposase -
SAI7S6_RS15660 2157014..2157172 + 159 WP_001792784.1 hypothetical protein -
SAI7S6_RS10850 2157830..2158687 - 858 WP_015445908.1 Cof-type HAD-IIB family hydrolase -
SAI7S6_RS10855 2158755..2159537 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T29115 WP_001802298.1 NC_020537:c2156334-2156230 [Staphylococcus aureus subsp. aureus ST228]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T29115 NC_020537:c2156334-2156230 [Staphylococcus aureus subsp. aureus ST228]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT29115 NC_020537:2156118-2156173 [Staphylococcus aureus subsp. aureus ST228]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References