Detailed information of TA system TA029107

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1834688..1834868
• Replicon: chromosome
• Accession: NC_020537
• Organism: Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAI7S6_RS15930
• Protein ID: WP_001801861.1
• Coordinates: 1834688..1834783 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1834811..1834868 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAI7S6_RS08865	1829851..1830501	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAI7S6_RS08870	1830582..1831577	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAI7S6_RS08875	1831652..1832278	+	627	WP_000669024.1	hypothetical protein	-
SAI7S6_RS08880	1832319..1832660	+	342	WP_000627540.1	DUF3969 family protein	-
SAI7S6_RS08885	1832761..1833333	+	573	WP_000414216.1	hypothetical protein	-
SAI7S6_RS15570	1833531..1834543	-	1013	Protein_1702	IS3 family transposase	-
SAI7S6_RS15930	1834688..1834783	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1834811..1834868	-	58	-	-	Antitoxin
SAI7S6_RS14715	1834906..1835007	+	102	WP_001792025.1	hypothetical protein	-
SAI7S6_RS15935	1834985..1835146	-	162	Protein_1705	transposase	-
SAI7S6_RS08910	1835137..1835631	-	495	Protein_1706	transposase	-
SAI7S6_RS08915	1836083..1837311	-	1229	Protein_1707	restriction endonuclease subunit S	-
SAI7S6_RS08920	1837304..1838859	-	1556	Protein_1708	type I restriction-modification system subunit M	-
SAI7S6_RS14720	1839023..1839157	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29107 WP_001801861.1 NC_020537:1834688-1834783 [Staphylococcus aureus subsp. aureus ST228]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29107 NC_020537:1834688-1834783 [Staphylococcus aureus subsp. aureus ST228]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29107 NC_020537:c1834868-1834811 [Staphylococcus aureus subsp. aureus ST228]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin