Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2156355..2156571 Replicon chromosome
Accession NC_020536
Organism Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAI6T6_RS14945 Protein ID WP_001802298.1
Coordinates 2156467..2156571 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2156355..2156410 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAI6T6_RS10820 2151914..2152291 - 378 WP_000361059.1 transposase -
SAI6T6_RS10825 2152298..2154190 - 1893 WP_001557544.1 site-specific integrase -
SAI6T6_RS10830 2154187..2155272 - 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
SAI6T6_RS10835 2155390..2156034 + 645 Protein_2043 transcriptional regulator -
- 2156355..2156410 + 56 - - Antitoxin
SAI6T6_RS14945 2156467..2156571 - 105 WP_001802298.1 hypothetical protein Toxin
SAI6T6_RS15710 2157251..2157409 + 159 WP_001792784.1 hypothetical protein -
SAI6T6_RS10845 2158067..2158924 - 858 WP_015445908.1 Cof-type HAD-IIB family hydrolase -
SAI6T6_RS10850 2158992..2159774 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T29100 WP_001802298.1 NC_020536:c2156571-2156467 [Staphylococcus aureus subsp. aureus ST228]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T29100 NC_020536:c2156571-2156467 [Staphylococcus aureus subsp. aureus ST228]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT29100 NC_020536:2156355-2156410 [Staphylococcus aureus subsp. aureus ST228]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References