Detailed information of TA system TA029092

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1834921..1835101
• Replicon: chromosome
• Accession: NC_020536
• Organism: Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAI6T6_RS15980
• Protein ID: WP_001801861.1
• Coordinates: 1834921..1835016 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1835044..1835101 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAI6T6_RS08860	1830084..1830734	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAI6T6_RS08865	1830815..1831810	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAI6T6_RS08870	1831885..1832511	+	627	WP_000669024.1	hypothetical protein	-
SAI6T6_RS08875	1832552..1832893	+	342	WP_000627540.1	DUF3969 family protein	-
SAI6T6_RS08880	1832994..1833566	+	573	WP_000414216.1	hypothetical protein	-
SAI6T6_RS15620	1833764..1834776	-	1013	Protein_1701	IS3 family transposase	-
SAI6T6_RS15980	1834921..1835016	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1835044..1835101	-	58	-	-	Antitoxin
SAI6T6_RS14765	1835139..1835240	+	102	WP_001792025.1	hypothetical protein	-
SAI6T6_RS15985	1835218..1835379	-	162	Protein_1704	transposase	-
SAI6T6_RS08905	1835370..1835864	-	495	Protein_1705	transposase	-
SAI6T6_RS08910	1836316..1837544	-	1229	Protein_1706	restriction endonuclease subunit S	-
SAI6T6_RS08915	1837537..1839092	-	1556	Protein_1707	type I restriction-modification system subunit M	-
SAI6T6_RS14770	1839256..1839390	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1810778..1909641	98863

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29092 WP_001801861.1 NC_020536:1834921-1835016 [Staphylococcus aureus subsp. aureus ST228]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29092 NC_020536:1834921-1835016 [Staphylococcus aureus subsp. aureus ST228]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29092 NC_020536:c1835101-1835044 [Staphylococcus aureus subsp. aureus ST228]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin