Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2441583..2441767 Replicon chromosome
Accession NC_020533
Organism Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag SAI4T8_RS12370 Protein ID WP_000482652.1
Coordinates 2441660..2441767 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2441583..2441643 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAI4T8_RS12345 2437038..2437205 - 168 Protein_2329 hypothetical protein -
SAI4T8_RS12355 2437436..2439169 - 1734 WP_000486483.1 ABC transporter ATP-binding protein/permease -
SAI4T8_RS12360 2439194..2440957 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2441583..2441643 + 61 - - Antitoxin
SAI4T8_RS12370 2441660..2441767 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
SAI4T8_RS12375 2441901..2442287 - 387 WP_000779360.1 flippase GtxA -
SAI4T8_RS12380 2442555..2443697 + 1143 WP_001176863.1 glycerate kinase -
SAI4T8_RS12385 2443757..2444416 + 660 WP_000831302.1 hypothetical protein -
SAI4T8_RS12390 2444598..2445809 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAI4T8_RS12395 2445932..2446405 - 474 WP_015445934.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T29088 WP_000482652.1 NC_020533:c2441767-2441660 [Staphylococcus aureus subsp. aureus ST228]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T29088 NC_020533:c2441767-2441660 [Staphylococcus aureus subsp. aureus ST228]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT29088 NC_020533:2441583-2441643 [Staphylococcus aureus subsp. aureus ST228]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References