Detailed information of TA system TA029077

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1834871..1835051
• Replicon: chromosome
• Accession: NC_020533
• Organism: Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAI4T8_RS14895
• Protein ID: WP_001801861.1
• Coordinates: 1834871..1834966 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1834994..1835051 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAI4T8_RS08870	1830034..1830684	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
SAI4T8_RS08875	1830765..1831760	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
SAI4T8_RS08880	1831835..1832461	+	627	WP_000669024.1	hypothetical protein	-
SAI4T8_RS08885	1832502..1832843	+	342	WP_000627540.1	DUF3969 family protein	-
SAI4T8_RS08890	1832944..1833516	+	573	WP_000414216.1	hypothetical protein	-
SAI4T8_RS14535	1833714..1834726	-	1013	Protein_1701	IS3 family transposase	-
SAI4T8_RS14895	1834871..1834966	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1834994..1835051	-	58	-	-	Antitoxin
SAI4T8_RS08910	1835089..1835190	+	102	WP_001792025.1	hypothetical protein	-
SAI4T8_RS14900	1835168..1835329	-	162	Protein_1704	transposase	-
SAI4T8_RS08915	1835320..1835814	-	495	Protein_1705	transposase	-
SAI4T8_RS08920	1836266..1837492	-	1227	Protein_1706	restriction endonuclease subunit S	-
SAI4T8_RS08925	1837485..1839041	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
SAI4T8_RS08930	1839205..1839339	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1810732..1861873	51141

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T29077 WP_001801861.1 NC_020533:1834871-1834966 [Staphylococcus aureus subsp. aureus ST228]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T29077 NC_020533:1834871-1834966 [Staphylococcus aureus subsp. aureus ST228]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT29077 NC_020533:c1835051-1834994 [Staphylococcus aureus subsp. aureus ST228]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin