Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2156665..2156881 Replicon chromosome
Accession NC_020532
Organism Staphylococcus aureus subsp. aureus ST228

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAI3T3_RS14960 Protein ID WP_001802298.1
Coordinates 2156777..2156881 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2156665..2156720 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAI3T3_RS10825 2152224..2152601 - 378 WP_000361059.1 transposase -
SAI3T3_RS10830 2152608..2154500 - 1893 WP_001557544.1 site-specific integrase -
SAI3T3_RS10835 2154497..2155582 - 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
SAI3T3_RS10840 2155700..2156344 + 645 Protein_2044 transcriptional regulator -
- 2156665..2156720 + 56 - - Antitoxin
SAI3T3_RS14960 2156777..2156881 - 105 WP_001802298.1 hypothetical protein Toxin
SAI3T3_RS15725 2157561..2157719 + 159 WP_001792784.1 hypothetical protein -
SAI3T3_RS10850 2158377..2159234 - 858 WP_015445908.1 Cof-type HAD-IIB family hydrolase -
SAI3T3_RS10855 2159302..2160084 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T29070 WP_001802298.1 NC_020532:c2156881-2156777 [Staphylococcus aureus subsp. aureus ST228]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T29070 NC_020532:c2156881-2156777 [Staphylococcus aureus subsp. aureus ST228]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT29070 NC_020532:2156665-2156720 [Staphylococcus aureus subsp. aureus ST228]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References