Detailed information of TA system TA290682

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 410374..410595
• Replicon: chromosome
• Accession: NZ_LR890334
• Organism: Escherichia coli isolate MINF_9A-sc-2280436

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A1D7PZ30
• Locus tag: JMW07_RS02110
• Protein ID: WP_022645587.1
• Coordinates: 410374..410481 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	410529..410595 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JMW07_RS02085	406218..407300	+	1083	WP_022645584.1	peptide chain release factor 1	-
JMW07_RS02090	407300..408133	+	834	WP_022645585.1	peptide chain release factor N(5)-glutamine methyltransferase	-
JMW07_RS02095	408130..408522	+	393	WP_000200374.1	invasion regulator SirB2	-
JMW07_RS02100	408526..409335	+	810	WP_022645586.1	invasion regulator SirB1	-
JMW07_RS02105	409371..410225	+	855	WP_000811065.1	3-deoxy-8-phosphooctulonate synthase	-
JMW07_RS02110	410374..410481	-	108	WP_022645587.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	410529..410595	+	67	NuclAT_28	-	Antitoxin
-	410529..410595	+	67	NuclAT_28	-	Antitoxin
-	410529..410595	+	67	NuclAT_28	-	Antitoxin
-	410529..410595	+	67	NuclAT_28	-	Antitoxin
-	410529..410595	+	67	NuclAT_30	-	Antitoxin
-	410529..410595	+	67	NuclAT_30	-	Antitoxin
-	410529..410595	+	67	NuclAT_30	-	Antitoxin
-	410529..410595	+	67	NuclAT_30	-	Antitoxin
-	410529..410595	+	67	NuclAT_32	-	Antitoxin
-	410529..410595	+	67	NuclAT_32	-	Antitoxin
-	410529..410595	+	67	NuclAT_32	-	Antitoxin
-	410529..410595	+	67	NuclAT_32	-	Antitoxin
-	410529..410595	+	67	NuclAT_34	-	Antitoxin
-	410529..410595	+	67	NuclAT_34	-	Antitoxin
-	410529..410595	+	67	NuclAT_34	-	Antitoxin
-	410529..410595	+	67	NuclAT_34	-	Antitoxin
-	410529..410595	+	67	NuclAT_36	-	Antitoxin
-	410529..410595	+	67	NuclAT_36	-	Antitoxin
-	410529..410595	+	67	NuclAT_36	-	Antitoxin
-	410529..410595	+	67	NuclAT_36	-	Antitoxin
-	410529..410595	+	67	NuclAT_38	-	Antitoxin
-	410529..410595	+	67	NuclAT_38	-	Antitoxin
-	410529..410595	+	67	NuclAT_38	-	Antitoxin
-	410529..410595	+	67	NuclAT_38	-	Antitoxin
-	410531..410588	+	58	NuclAT_41	-	-
-	410531..410588	+	58	NuclAT_41	-	-
-	410531..410588	+	58	NuclAT_41	-	-
-	410531..410588	+	58	NuclAT_41	-	-
-	410531..410588	+	58	NuclAT_43	-	-
-	410531..410588	+	58	NuclAT_43	-	-
-	410531..410588	+	58	NuclAT_43	-	-
-	410531..410588	+	58	NuclAT_43	-	-
-	410531..410588	+	58	NuclAT_45	-	-
-	410531..410588	+	58	NuclAT_45	-	-
-	410531..410588	+	58	NuclAT_45	-	-
-	410531..410588	+	58	NuclAT_45	-	-
-	410531..410588	+	58	NuclAT_47	-	-
-	410531..410588	+	58	NuclAT_47	-	-
-	410531..410588	+	58	NuclAT_47	-	-
-	410531..410588	+	58	NuclAT_47	-	-
JMW07_RS02115	410909..411016	-	108	WP_000170956.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	411069..411130	+	62	NuclAT_40	-	-
-	411069..411130	+	62	NuclAT_40	-	-
-	411069..411130	+	62	NuclAT_40	-	-
-	411069..411130	+	62	NuclAT_40	-	-
-	411069..411130	+	62	NuclAT_42	-	-
-	411069..411130	+	62	NuclAT_42	-	-
-	411069..411130	+	62	NuclAT_42	-	-
-	411069..411130	+	62	NuclAT_42	-	-
-	411069..411130	+	62	NuclAT_44	-	-
-	411069..411130	+	62	NuclAT_44	-	-
-	411069..411130	+	62	NuclAT_44	-	-
-	411069..411130	+	62	NuclAT_44	-	-
-	411069..411130	+	62	NuclAT_46	-	-
-	411069..411130	+	62	NuclAT_46	-	-
-	411069..411130	+	62	NuclAT_46	-	-
-	411069..411130	+	62	NuclAT_46	-	-
-	411069..411131	+	63	NuclAT_29	-	-
-	411069..411131	+	63	NuclAT_29	-	-
-	411069..411131	+	63	NuclAT_29	-	-
-	411069..411131	+	63	NuclAT_29	-	-
-	411069..411131	+	63	NuclAT_31	-	-
-	411069..411131	+	63	NuclAT_31	-	-
-	411069..411131	+	63	NuclAT_31	-	-
-	411069..411131	+	63	NuclAT_31	-	-
-	411069..411131	+	63	NuclAT_33	-	-
-	411069..411131	+	63	NuclAT_33	-	-
-	411069..411131	+	63	NuclAT_33	-	-
-	411069..411131	+	63	NuclAT_33	-	-
-	411069..411131	+	63	NuclAT_35	-	-
-	411069..411131	+	63	NuclAT_35	-	-
-	411069..411131	+	63	NuclAT_35	-	-
-	411069..411131	+	63	NuclAT_35	-	-
-	411069..411131	+	63	NuclAT_37	-	-
-	411069..411131	+	63	NuclAT_37	-	-
-	411069..411131	+	63	NuclAT_37	-	-
-	411069..411131	+	63	NuclAT_37	-	-
-	411069..411131	+	63	NuclAT_39	-	-
-	411069..411131	+	63	NuclAT_39	-	-
-	411069..411131	+	63	NuclAT_39	-	-
-	411069..411131	+	63	NuclAT_39	-	-
JMW07_RS02120	411422..412522	-	1101	WP_001301956.1	sodium-potassium/proton antiporter ChaA	-
JMW07_RS02125	412792..413022	+	231	WP_001146444.1	putative cation transport regulator ChaB	-
JMW07_RS02130	413180..413875	+	696	WP_012311798.1	glutathione-specific gamma-glutamylcyclotransferase	-
JMW07_RS02135	413919..414272	-	354	WP_001169659.1	DsrE/F sulfur relay family protein YchN	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4029.82 Da
• Isoelectric Point: 11.4779

>T290682 WP_022645587.1 NZ_LR890334:c410481-410374 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAVIVSWWRNRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT290682 NZ_LR890334:410529-410595 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGGGTTCTC

Structures

Toxin

• AlphaFold DB: A0A1D7PZ30

Antitoxin