Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 2531998..2532611 Replicon chromosome
Accession NZ_LR882950
Organism Planktothrix agardhii strain PCC7805

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag NMG85_RS11505 Protein ID WP_235752057.1
Coordinates 2531998..2532282 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NMG85_RS11510 Protein ID WP_235752056.1
Coordinates 2532297..2532611 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG85_RS11475 (PCC7805_02307) 2528827..2529048 + 222 WP_227381101.1 hypothetical protein -
NMG85_RS11480 (PCC7805_02308) 2529070..2529282 + 213 WP_042156661.1 hypothetical protein -
NMG85_RS11485 (PCC7805_02309) 2529416..2529733 + 318 WP_235752061.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
NMG85_RS11490 (PCC7805_02310) 2529733..2530011 + 279 WP_235752060.1 type II toxin-antitoxin system RelE/ParE family toxin -
NMG85_RS11495 (PCC7805_02311) 2530054..2531292 + 1239 WP_042156657.1 ATP-binding protein -
NMG85_RS11500 (PCC7805_02312) 2531282..2531860 + 579 WP_235752058.1 DUF4276 family protein -
NMG85_RS11505 (PCC7805_02313) 2531998..2532282 + 285 WP_235752057.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NMG85_RS11510 (PCC7805_02314) 2532297..2532611 + 315 WP_235752056.1 HigA family addiction module antitoxin Antitoxin
NMG85_RS11515 (PCC7805_02315) 2532677..2533252 - 576 WP_235752055.1 Uma2 family endonuclease -
NMG85_RS11520 (PCC7805_02316) 2533367..2533708 - 342 WP_235752054.1 type II toxin-antitoxin system PemK/MazF family toxin -
NMG85_RS11525 (PCC7805_02317) 2533705..2533938 - 234 WP_042156647.1 hypothetical protein -
NMG85_RS11530 (PCC7805_02319) 2534749..2535333 + 585 WP_235766119.1 transposase -
NMG85_RS11535 (PCC7805_02320) 2535462..2536037 - 576 WP_235766118.1 Uma2 family endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(15-57)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11221.74 Da        Isoelectric Point: 9.7476

>T289975 WP_235752057.1 NZ_LR882950:2531998-2532282 [Planktothrix agardhii]
MPQKYKDKRTAKFAAGDRVKEFQAFERQAYKRLEILEAAPNKESLKALPSNRFEALGGDRKGQYSIRINDKWRICFEWTE
TENRPFHIEIVDYH

Download         Length: 285 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11568.18 Da        Isoelectric Point: 5.6957

>AT289975 WP_235752056.1 NZ_LR882950:2532297-2532611 [Planktothrix agardhii]
MARPAIHPGEILSDELEELGISASELARSLHIPTNRITQILKGQRGITADTALRLGRWFGTGAELWLNLQKTYELRLAQE
LAGEEIQNTIQPRSSINNQPLVQV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References