Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3683472..3683694 Replicon chromosome
Accession NZ_LR881938
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag IEU92_RS17860 Protein ID WP_000141634.1
Coordinates 3683472..3683579 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3683628..3683694 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IEU92_RS17835 3678725..3679477 - 753 Protein_3480 cellulose biosynthesis protein BcsQ -
IEU92_RS17840 3679489..3679677 - 189 WP_001063318.1 YhjR family protein -
IEU92_RS17845 3679950..3681521 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
IEU92_RS17850 3681518..3681709 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
IEU92_RS17855 3681706..3683385 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
IEU92_RS17860 3683472..3683579 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3683628..3683694 + 67 - - Antitoxin
IEU92_RS17865 3684055..3685326 + 1272 WP_001295225.1 transporter -
IEU92_RS17870 3685356..3686360 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
IEU92_RS17875 3686357..3687340 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
IEU92_RS17880 3687351..3688253 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T289528 WP_000141634.1 NZ_LR881938:c3683579-3683472 [Escherichia coli str. K-12 substr. MG1655]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT289528 NZ_LR881938:3683628-3683694 [Escherichia coli str. K-12 substr. MG1655]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References