Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2767950..2768228 Replicon chromosome
Accession NZ_LR822061
Organism Staphylococcus aureus isolate HU-14

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag BKMNNEJI_RS13805 Protein ID WP_001802298.1
Coordinates 2767950..2768054 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2768050..2768228 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKMNNEJI_RS13790 2764747..2765529 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
BKMNNEJI_RS13795 2765597..2766454 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
BKMNNEJI_RS13800 2767112..2767270 - 159 WP_001792784.1 hypothetical protein -
BKMNNEJI_RS13805 2767950..2768054 + 105 WP_001802298.1 hypothetical protein Toxin
- 2768050..2768228 - 179 - - Antitoxin
BKMNNEJI_RS13810 2768487..2769578 - 1092 WP_000495669.1 hypothetical protein -
BKMNNEJI_RS13815 2769844..2770821 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
BKMNNEJI_RS13820 2770823..2771143 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BKMNNEJI_RS13825 2771295..2771960 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T289419 WP_001802298.1 NZ_LR822061:2767950-2768054 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 179 bp

>AT289419 NZ_LR822061:c2768228-2768050 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References