Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2481579..2481763 Replicon chromosome
Accession NZ_LR822060
Organism Staphylococcus aureus isolate P3.1

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag LJDFIFNA_RS12335 Protein ID WP_000482652.1
Coordinates 2481579..2481686 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2481703..2481763 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJDFIFNA_RS12310 2476941..2477414 + 474 WP_000456486.1 GyrI-like domain-containing protein -
LJDFIFNA_RS12315 2477537..2478748 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
LJDFIFNA_RS12320 2478930..2479589 - 660 WP_000831302.1 hypothetical protein -
LJDFIFNA_RS12325 2479649..2480791 - 1143 WP_001176863.1 glycerate kinase -
LJDFIFNA_RS12330 2481059..2481445 + 387 WP_000779360.1 flippase GtxA -
LJDFIFNA_RS12335 2481579..2481686 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2481703..2481763 - 61 - - Antitoxin
LJDFIFNA_RS12340 2482389..2484152 + 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
LJDFIFNA_RS12345 2484177..2485910 + 1734 WP_000486483.1 ABC transporter ATP-binding protein/permease -
LJDFIFNA_RS12350 2486141..2486308 + 168 Protein_2401 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T289396 WP_000482652.1 NZ_LR822060:2481579-2481686 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT289396 NZ_LR822060:c2481763-2481703 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References