Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4101377..4102176 Replicon chromosome
Accession NZ_LR778146
Organism Escherichia coli isolate SC455

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag H1D08_RS19910 Protein ID WP_087598199.1
Coordinates 4101377..4101841 (-) Length 155 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag H1D08_RS19915 Protein ID WP_087598198.1
Coordinates 4101841..4102176 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1D08_RS19880 4096378..4096812 - 435 WP_137527029.1 PTS sugar transporter subunit IIA -
H1D08_RS19885 4096830..4097708 - 879 WP_001298314.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
H1D08_RS19890 4097698..4098477 - 780 WP_000406214.1 PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC -
H1D08_RS19895 4098488..4098961 - 474 WP_001298322.1 PTS N-acetylgalactosamine transporter subunit IIB -
H1D08_RS19900 4098984..4100264 - 1281 WP_137527028.1 tagatose-bisphosphate aldolase subunit KbaZ -
H1D08_RS19905 4100513..4101322 + 810 WP_000072187.1 aga operon transcriptional regulator AgaR -
H1D08_RS19910 4101377..4101841 - 465 WP_087598199.1 type II toxin-antitoxin system ribonuclease toxin YhaV Toxin
H1D08_RS19915 4101841..4102176 - 336 WP_087598198.1 type II toxin-antitoxin system antitoxin PrlF Antitoxin
H1D08_RS19920 4102325..4103896 - 1572 WP_001273940.1 galactarate dehydratase -
H1D08_RS19925 4104271..4105605 + 1335 WP_000979025.1 galactarate/glucarate/glycerate transporter GarP -
H1D08_RS19930 4105621..4106391 + 771 WP_001058227.1 2-dehydro-3-deoxyglucarate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(14-110)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17811.16 Da        Isoelectric Point: 9.4947

>T289184 WP_087598199.1 NZ_LR778146:c4101841-4101377 [Escherichia coli]
MDFPQRVNGWALYAHPCFQETYDAFVAEVEALKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRYRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH

Download         Length: 465 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12303.88 Da        Isoelectric Point: 4.5392

>AT289184 WP_087598198.1 NZ_LR778146:c4102176-4101841 [Escherichia coli]
MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHYEILPGGQVFLCRLGDEQEDHTMNAFLRFLDADIQNN
PQKTRPFDIQQGKKLVAGMDVNIDDEIGDDE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References