Detailed information of TA system TA289152

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 4269538..4269758
• Replicon: chromosome
• Accession: NZ_LR778143
• Organism: Escherichia coli isolate SC422

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: B7LGX8
• Locus tag: H1C98_RS20485
• Protein ID: WP_000170965.1
• Coordinates: 4269651..4269758 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	4269538..4269604 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H1C98_RS20460	4264817..4266211	-	1395	WP_000086201.1	inverse autotransporter invasin YchO	-
H1C98_RS20465	4266396..4266749	+	354	WP_001169669.1	DsrE/F sulfur relay family protein YchN	-
H1C98_RS20470	4266793..4267488	-	696	WP_001297117.1	glutathione-specific gamma-glutamylcyclotransferase	-
H1C98_RS20475	4267646..4267876	-	231	WP_001146442.1	putative cation transport regulator ChaB	-
H1C98_RS20480	4268146..4269246	+	1101	WP_001295620.1	sodium-potassium/proton antiporter ChaA	-
-	4269538..4269604	-	67	-	-	Antitoxin
H1C98_RS20485	4269651..4269758	+	108	WP_000170965.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4270071..4270134	-	64	NuclAT_33	-	-
-	4270071..4270134	-	64	NuclAT_33	-	-
-	4270071..4270134	-	64	NuclAT_33	-	-
-	4270071..4270134	-	64	NuclAT_33	-	-
-	4270071..4270134	-	64	NuclAT_36	-	-
-	4270071..4270134	-	64	NuclAT_36	-	-
-	4270071..4270134	-	64	NuclAT_36	-	-
-	4270071..4270134	-	64	NuclAT_36	-	-
-	4270071..4270134	-	64	NuclAT_39	-	-
-	4270071..4270134	-	64	NuclAT_39	-	-
-	4270071..4270134	-	64	NuclAT_39	-	-
-	4270071..4270134	-	64	NuclAT_39	-	-
-	4270071..4270134	-	64	NuclAT_42	-	-
-	4270071..4270134	-	64	NuclAT_42	-	-
-	4270071..4270134	-	64	NuclAT_42	-	-
-	4270071..4270134	-	64	NuclAT_42	-	-
-	4270071..4270134	-	64	NuclAT_45	-	-
-	4270071..4270134	-	64	NuclAT_45	-	-
-	4270071..4270134	-	64	NuclAT_45	-	-
-	4270071..4270134	-	64	NuclAT_45	-	-
-	4270071..4270134	-	64	NuclAT_48	-	-
-	4270071..4270134	-	64	NuclAT_48	-	-
-	4270071..4270134	-	64	NuclAT_48	-	-
-	4270071..4270134	-	64	NuclAT_48	-	-
-	4270072..4270134	-	63	NuclAT_50	-	-
-	4270072..4270134	-	63	NuclAT_50	-	-
-	4270072..4270134	-	63	NuclAT_50	-	-
-	4270072..4270134	-	63	NuclAT_50	-	-
-	4270072..4270134	-	63	NuclAT_53	-	-
-	4270072..4270134	-	63	NuclAT_53	-	-
-	4270072..4270134	-	63	NuclAT_53	-	-
-	4270072..4270134	-	63	NuclAT_53	-	-
-	4270072..4270134	-	63	NuclAT_56	-	-
-	4270072..4270134	-	63	NuclAT_56	-	-
-	4270072..4270134	-	63	NuclAT_56	-	-
-	4270072..4270134	-	63	NuclAT_56	-	-
-	4270073..4270134	-	62	NuclAT_15	-	-
-	4270073..4270134	-	62	NuclAT_15	-	-
-	4270073..4270134	-	62	NuclAT_15	-	-
-	4270073..4270134	-	62	NuclAT_15	-	-
-	4270073..4270134	-	62	NuclAT_18	-	-
-	4270073..4270134	-	62	NuclAT_18	-	-
-	4270073..4270134	-	62	NuclAT_18	-	-
-	4270073..4270134	-	62	NuclAT_18	-	-
-	4270073..4270134	-	62	NuclAT_21	-	-
-	4270073..4270134	-	62	NuclAT_21	-	-
-	4270073..4270134	-	62	NuclAT_21	-	-
-	4270073..4270134	-	62	NuclAT_21	-	-
-	4270073..4270134	-	62	NuclAT_24	-	-
-	4270073..4270134	-	62	NuclAT_24	-	-
-	4270073..4270134	-	62	NuclAT_24	-	-
-	4270073..4270134	-	62	NuclAT_24	-	-
-	4270073..4270134	-	62	NuclAT_27	-	-
-	4270073..4270134	-	62	NuclAT_27	-	-
-	4270073..4270134	-	62	NuclAT_27	-	-
-	4270073..4270134	-	62	NuclAT_27	-	-
-	4270073..4270134	-	62	NuclAT_30	-	-
-	4270073..4270134	-	62	NuclAT_30	-	-
-	4270073..4270134	-	62	NuclAT_30	-	-
-	4270073..4270134	-	62	NuclAT_30	-	-
H1C98_RS20490	4270187..4270294	+	108	WP_000170926.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	4270607..4270672	-	66	NuclAT_32	-	-
-	4270607..4270672	-	66	NuclAT_32	-	-
-	4270607..4270672	-	66	NuclAT_32	-	-
-	4270607..4270672	-	66	NuclAT_32	-	-
-	4270607..4270672	-	66	NuclAT_35	-	-
-	4270607..4270672	-	66	NuclAT_35	-	-
-	4270607..4270672	-	66	NuclAT_35	-	-
-	4270607..4270672	-	66	NuclAT_35	-	-
-	4270607..4270672	-	66	NuclAT_38	-	-
-	4270607..4270672	-	66	NuclAT_38	-	-
-	4270607..4270672	-	66	NuclAT_38	-	-
-	4270607..4270672	-	66	NuclAT_38	-	-
-	4270607..4270672	-	66	NuclAT_41	-	-
-	4270607..4270672	-	66	NuclAT_41	-	-
-	4270607..4270672	-	66	NuclAT_41	-	-
-	4270607..4270672	-	66	NuclAT_41	-	-
-	4270607..4270672	-	66	NuclAT_44	-	-
-	4270607..4270672	-	66	NuclAT_44	-	-
-	4270607..4270672	-	66	NuclAT_44	-	-
-	4270607..4270672	-	66	NuclAT_44	-	-
-	4270607..4270672	-	66	NuclAT_47	-	-
-	4270607..4270672	-	66	NuclAT_47	-	-
-	4270607..4270672	-	66	NuclAT_47	-	-
-	4270607..4270672	-	66	NuclAT_47	-	-
-	4270608..4270674	-	67	NuclAT_49	-	-
-	4270608..4270674	-	67	NuclAT_49	-	-
-	4270608..4270674	-	67	NuclAT_49	-	-
-	4270608..4270674	-	67	NuclAT_49	-	-
-	4270608..4270674	-	67	NuclAT_52	-	-
-	4270608..4270674	-	67	NuclAT_52	-	-
-	4270608..4270674	-	67	NuclAT_52	-	-
-	4270608..4270674	-	67	NuclAT_52	-	-
-	4270608..4270674	-	67	NuclAT_55	-	-
-	4270608..4270674	-	67	NuclAT_55	-	-
-	4270608..4270674	-	67	NuclAT_55	-	-
-	4270608..4270674	-	67	NuclAT_55	-	-
-	4270609..4270672	-	64	NuclAT_14	-	-
-	4270609..4270672	-	64	NuclAT_14	-	-
-	4270609..4270672	-	64	NuclAT_14	-	-
-	4270609..4270672	-	64	NuclAT_14	-	-
-	4270609..4270672	-	64	NuclAT_17	-	-
-	4270609..4270672	-	64	NuclAT_17	-	-
-	4270609..4270672	-	64	NuclAT_17	-	-
-	4270609..4270672	-	64	NuclAT_17	-	-
-	4270609..4270672	-	64	NuclAT_20	-	-
-	4270609..4270672	-	64	NuclAT_20	-	-
-	4270609..4270672	-	64	NuclAT_20	-	-
-	4270609..4270672	-	64	NuclAT_20	-	-
-	4270609..4270672	-	64	NuclAT_23	-	-
-	4270609..4270672	-	64	NuclAT_23	-	-
-	4270609..4270672	-	64	NuclAT_23	-	-
-	4270609..4270672	-	64	NuclAT_23	-	-
-	4270609..4270672	-	64	NuclAT_26	-	-
-	4270609..4270672	-	64	NuclAT_26	-	-
-	4270609..4270672	-	64	NuclAT_26	-	-
-	4270609..4270672	-	64	NuclAT_26	-	-
-	4270609..4270672	-	64	NuclAT_29	-	-
-	4270609..4270672	-	64	NuclAT_29	-	-
-	4270609..4270672	-	64	NuclAT_29	-	-
-	4270609..4270672	-	64	NuclAT_29	-	-
H1C98_RS20495	4270722..4270829	+	108	WP_000170954.1	type I toxin-antitoxin system toxin Ldr family protein	-
H1C98_RS20500	4270978..4271832	-	855	WP_000811065.1	3-deoxy-8-phosphooctulonate synthase	-
H1C98_RS20505	4271868..4272677	-	810	WP_001257044.1	invasion regulator SirB1	-
H1C98_RS20510	4272681..4273073	-	393	WP_000200392.1	invasion regulator SirB2	-
H1C98_RS20515	4273070..4273903	-	834	WP_000456467.1	peptide chain release factor N(5)-glutamine methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4001.77 Da
• Isoelectric Point: 11.4779

>T289152 WP_000170965.1 NZ_LR778143:4269651-4269758 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVSWWRNRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT289152 NZ_LR778143:c4269604-4269538 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Structures

Toxin

• AlphaFold DB: A0A0E0Y029

Antitoxin