Detailed information of TA system TA288975

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 5051584..5051996
• Replicon: chromosome
• Accession: NZ_LR740758
• Organism: Escherichia coli strain BEN5202 isolate laying hen 51 weeks old

Toxin (Protein)

• Gene name: symE
• Uniprot ID: A0A8E0IWC4
• Locus tag: APEC5202_RS24565
• Protein ID: WP_001513534.1
• Coordinates: 5051584..5051925 (-)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	5051920..5051996 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APEC5202_RS24545	5046653..5047933	-	1281	WP_001338077.1	DUF445 domain-containing protein	-
APEC5202_RS24550	5048118..5049038	+	921	WP_001513532.1	Rpn family recombination-promoting nuclease/putative transposase	-
APEC5202_RS24555	5049266..5049346	+	81	WP_020233658.1	hypothetical protein	-
APEC5202_RS24560	5049381..5051537	+	2157	WP_174235638.1	DUF262 domain-containing protein	-
APEC5202_RS24565	5051584..5051925	-	342	WP_001513534.1	endoribonuclease SymE	Toxin
-	5051920..5051996	+	77	NuclAT_6	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_6	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_6	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_6	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_7	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_7	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_7	-	Antitoxin
-	5051920..5051996	+	77	NuclAT_7	-	Antitoxin
APEC5202_RS24570	5052146..5053915	-	1770	WP_001513535.1	restriction endonuclease subunit S	-
APEC5202_RS24575	5053915..5055384	-	1470	WP_001387312.1	type I restriction-modification system subunit M	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12247.03 Da
• Isoelectric Point: 7.8545

>T288975 WP_001513534.1 NZ_LR740758:c5051925-5051584 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRQLTVSYASHYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

Antitoxin

Nucleotide

• Length: 77 bp

>AT288975 NZ_LR740758:5051920-5051996 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin