Detailed information of TA system TA288967

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 3980038..3980260
• Replicon: chromosome
• Accession: NZ_LR740758
• Organism: Escherichia coli strain BEN5202 isolate laying hen 51 weeks old

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: APEC5202_RS19410
• Protein ID: WP_001295224.1
• Coordinates: 3980038..3980145 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	3980202..3980260 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APEC5202_RS19385	3975292..3976044	-	753	WP_000279545.1	cellulose biosynthesis protein BcsQ	-
APEC5202_RS19390	3976056..3976244	-	189	WP_001063314.1	YhjR family protein	-
APEC5202_RS19395	3976517..3978088	+	1572	WP_001204957.1	cellulose biosynthesis protein BcsE	-
APEC5202_RS19400	3978085..3978276	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
APEC5202_RS19405	3978273..3979952	+	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
APEC5202_RS19410	3980038..3980145	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	3980202..3980260	+	59	-	-	Antitoxin
APEC5202_RS19415	3980521..3980628	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
APEC5202_RS19420	3981003..3981110	-	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	-
APEC5202_RS19425	3981586..3982857	+	1272	WP_001332306.1	amino acid permease	-
APEC5202_RS19430	3982887..3983891	-	1005	WP_000103579.1	dipeptide ABC transporter ATP-binding subunit DppF	-
APEC5202_RS19435	3983888..3984871	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T288967 WP_001295224.1 NZ_LR740758:c3980145-3980038 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT288967 NZ_LR740758:3980202-3980260 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin