Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1328996..1329645 Replicon chromosome
Accession NZ_LR699009
Organism Pluralibacter gergoviae isolate MGYG-HGUT-02520

Toxin (Protein)


Gene name higB Uniprot ID A0A1S2BAV2
Locus tag FYC31_RS06350 Protein ID WP_048254040.1
Coordinates 1328996..1329337 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FYC31_RS06355 Protein ID WP_048253972.1
Coordinates 1329334..1329645 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC31_RS06325 1324362..1325804 - 1443 WP_048253975.1 PTS N-acetylmuramic acid transporter subunit IIBC -
FYC31_RS06330 1325807..1326718 - 912 WP_048253974.1 N-acetylmuramic acid 6-phosphate etherase -
FYC31_RS06335 1326835..1327722 - 888 WP_048254041.1 LysR family transcriptional regulator -
FYC31_RS06340 1327825..1328235 + 411 WP_048253973.1 CidA/LrgA family protein -
FYC31_RS06345 1328228..1328917 + 690 WP_043081728.1 LrgB family protein -
FYC31_RS06350 1328996..1329337 + 342 WP_048254040.1 hypothetical protein Toxin
FYC31_RS06355 1329334..1329645 + 312 WP_048253972.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FYC31_RS06360 1329685..1331334 - 1650 WP_106912782.1 cation/acetate symporter ActP -
FYC31_RS06365 1331334..1331645 - 312 WP_043081730.1 DUF485 domain-containing protein -
FYC31_RS06370 1331868..1333826 - 1959 WP_048253970.1 acetate--CoA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(30-99)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13422.37 Da        Isoelectric Point: 9.7299

>T288756 WP_048254040.1 NZ_LR699009:1328996-1329337 [Pluralibacter gergoviae]
MDALFIELPPFERHRAEYFSDDDFKAFQQMLLHNPCAGDVIRGAGGLRKIRFADPRRNKGKRGGIRVIYYWYAEKSHFLL
FTLYDKEQQDDLTAHQRNILSHLLEQAKQRIIR

Download         Length: 342 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11596.36 Da        Isoelectric Point: 10.0436

>AT288756 WP_048253972.1 NZ_LR699009:1329334-1329645 [Pluralibacter gergoviae]
VTKRDIFSELQEGIEAWGELNAGKKTLRTHRVNTRDLAIAPEDLVKVREQLNLSQAVFARYLHAGLKTYQNWEQGLASPN
KQAVLLIRMIEKSPSVLSQLAAI

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S2BAV2

Antitoxin

Source ID Structure

References