Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 461045..461308 Replicon chromosome
Accession NZ_LR699008
Organism Hafnia alvei isolate MGYG-HGUT-02508

Toxin (Protein)


Gene name hokH Uniprot ID A0A1C6YY26
Locus tag FYB81_RS02095 Protein ID WP_025798685.1
Coordinates 461150..461308 (+) Length 53 a.a.

Antitoxin (RNA)


Gene name sokH
Locus tag -
Coordinates 461045..461102 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYB81_RS02075 456260..457330 - 1071 WP_111328966.1 dihydroxyacetone kinase subunit DhaK -
FYB81_RS02080 457430..458530 - 1101 WP_111328967.1 glycerol dehydrogenase -
FYB81_RS02085 459036..459719 + 684 WP_043490623.1 DUF1190 family protein -
FYB81_RS02090 459722..460882 + 1161 WP_025798684.1 glutathionylspermidine synthase family protein -
- 461045..461102 - 58 - - Antitoxin
FYB81_RS02095 461150..461308 + 159 WP_025798685.1 Hok/Gef family protein Toxin
FYB81_RS02100 461469..463688 - 2220 WP_025798687.1 lysine decarboxylase -
FYB81_RS02105 463794..465122 - 1329 WP_111328968.1 cadaverine/lysine antiporter -
FYB81_RS02110 465616..466149 + 534 WP_111328969.1 SprT family zinc-dependent metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-46)


Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6065.37 Da        Isoelectric Point: 9.2226

>T288741 WP_025798685.1 NZ_LR699008:461150-461308 [Hafnia alvei]
MSRKLLLYGLIVMCFTLLIFTWMVRGSLCELRIKQGKTEVAAFLNYEDKHAL

Download         Length: 159 bp

Antitoxin


Download         Length: 58 bp

>AT288741 NZ_LR699008:c461102-461045 [Hafnia alvei]
GTTCAGATGTGGTTAGGATTGCCTCAGGTTAATGAAAATTGACCTGGGGCTTTTACTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C6YY26

Antitoxin

Download structure file

References