Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2721205..2721541 Replicon chromosome
Accession NZ_LR698844
Organism Enterococcus faecalis isolate MGYG-HGUT-01694

Toxin (Protein)


Gene name txpA Uniprot ID E2Z0W4
Locus tag FXY61_RS13325 Protein ID WP_002381035.1
Coordinates 2721205..2721348 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2721492..2721541 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXY61_RS13305 2717297..2717935 - 639 WP_015212268.1 lytic polysaccharide monooxygenase -
FXY61_RS13310 2718621..2720237 + 1617 WP_015212269.1 phosphatase PAP2/LCP family protein -
FXY61_RS13315 2720566..2720715 + 150 WP_002411240.1 putative holin-like toxin -
FXY61_RS13320 2720834..2720974 + 141 WP_073340360.1 putative holin-like toxin -
FXY61_RS13325 2721205..2721348 + 144 WP_002381035.1 putative holin-like toxin Toxin
- 2721492..2721541 + 50 - - Antitoxin
FXY61_RS13330 2721543..2725370 - 3828 WP_002389430.1 WxL domain-containing protein -
FXY61_RS13335 2725357..2725719 - 363 WP_002378868.1 LPXTG cell wall anchor domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5202.20 Da        Isoelectric Point: 10.0041

>T288682 WP_002381035.1 NZ_LR698844:2721205-2721348 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 50 bp

>AT288682 NZ_LR698844:2721492-2721541 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z6BWH2

Antitoxin

Download structure file

References