Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2638474..2638736 Replicon chromosome
Accession NZ_LR698844
Organism Enterococcus faecalis isolate MGYG-HGUT-01694

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag FXY61_RS12955 Protein ID WP_002367458.1
Coordinates 2638593..2638736 (-) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2638474..2638660 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXY61_RS12940 2633931..2636675 + 2745 WP_002411259.1 glycoside hydrolase family 65 protein -
FXY61_RS12945 2636690..2637340 + 651 WP_002389419.1 beta-phosphoglucomutase -
FXY61_RS12950 2637760..2638353 + 594 WP_002389391.1 hypothetical protein -
- 2638474..2638660 + 187 - - Antitoxin
FXY61_RS12955 2638593..2638736 - 144 WP_002367458.1 putative holin-like toxin Toxin
FXY61_RS12960 2638968..2639939 - 972 WP_002381060.1 ribose-phosphate diphosphokinase -
FXY61_RS12965 2640114..2640551 - 438 WP_002389480.1 peptide-methionine (R)-S-oxide reductase MsrB -
FXY61_RS12970 2640684..2641238 - 555 WP_002389433.1 septum formation protein Maf -
FXY61_RS12975 2641263..2643395 - 2133 WP_002389406.1 DNA mismatch repair endonuclease MutL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5311.50 Da        Isoelectric Point: 10.8331

>T288669 WP_002367458.1 NZ_LR698844:c2638736-2638593 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp

Antitoxin


Download         Length: 187 bp

>AT288669 NZ_LR698844:2638474-2638660 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References