288553

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2765115..2765441 Replicon chromosome
Accession NZ_LR594051
Organism Enterococcus faecalis strain NCTC8732

Toxin (Protein)


Gene name txpA Uniprot ID A0A3N3Z2N6
Locus tag FGL29_RS14375 Protein ID WP_073340360.1
Coordinates 2765301..2765441 (+) Length 47 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2765115..2765299 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL29_RS14345 2760161..2760376 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
FGL29_RS14350 2760515..2761507 + 993 WP_002354765.1 biotin--[acetyl-CoA-carboxylase] ligase -
FGL29_RS14355 2761771..2762400 - 630 WP_002354763.1 lytic polysaccharide monooxygenase -
FGL29_RS14365 2763093..2764709 + 1617 WP_002381036.1 phosphatase PAP2/LCP family protein -
FGL29_RS14370 2765039..2765182 + 144 WP_002392818.1 putative holin-like toxin -
- 2765115..2765299 - 185 - - Antitoxin
FGL29_RS14375 2765301..2765441 + 141 WP_073340360.1 putative holin-like toxin Toxin
FGL29_RS14380 2765667..2765810 + 144 WP_002381035.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-46)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5218.33 Da        Isoelectric Point: 10.3265

>T288553 WP_073340360.1 NZ_LR594051:2765301-2765441 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 141 bp

Antitoxin


Download         Length: 185 bp

>AT288553 NZ_LR594051:c2765299-2765115 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N3Z2N6

Antitoxin

Download structure file

References