Detailed information of TA system TA288550

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2765039..2765299
• Replicon: chromosome
• Accession: NZ_LR594051
• Organism: Enterococcus faecalis strain NCTC8732

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: FGL29_RS14370
• Protein ID: WP_002392818.1
• Coordinates: 2765039..2765182 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2765115..2765299 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGL29_RS14345	2760161..2760376	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
FGL29_RS14350	2760515..2761507	+	993	WP_002354765.1	biotin--[acetyl-CoA-carboxylase] ligase	-
FGL29_RS14355	2761771..2762400	-	630	WP_002354763.1	lytic polysaccharide monooxygenase	-
FGL29_RS14365	2763093..2764709	+	1617	WP_002381036.1	phosphatase PAP2/LCP family protein	-
FGL29_RS14370	2765039..2765182	+	144	WP_002392818.1	putative holin-like toxin	Toxin
-	2765115..2765299	-	185	-	-	Antitoxin
FGL29_RS14375	2765301..2765441	+	141	WP_073340360.1	putative holin-like toxin	-
FGL29_RS14380	2765667..2765810	+	144	WP_002381035.1	putative holin-like toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5344.49 Da
• Isoelectric Point: 10.6323

>T288550 WP_002392818.1 NZ_LR594051:2765039-2765182 [Enterococcus faecalis]
MNVSTKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT288550 NZ_LR594051:c2765299-2765115 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin