Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2193270..2193924 Replicon chromosome
Accession NZ_LR590482
Organism Pseudomonas synxantha strain NCTC10696

Toxin (Protein)


Gene name higB Uniprot ID A0A0R2YXS2
Locus tag FGL41_RS10250 Protein ID WP_057024311.1
Coordinates 2193574..2193924 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0W0N117
Locus tag FGL41_RS10245 Protein ID WP_014718915.1
Coordinates 2193270..2193584 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL41_RS10210 2188940..2190070 + 1131 WP_057024307.1 MFS transporter -
FGL41_RS10215 2190078..2190599 - 522 WP_057024308.1 DUF3087 domain-containing protein -
FGL41_RS10220 2190714..2190893 + 180 WP_046068648.1 hypothetical protein -
FGL41_RS10225 2190906..2191112 + 207 WP_046068647.1 hypothetical protein -
FGL41_RS10230 2191143..2191379 - 237 WP_005789137.1 hypothetical protein -
FGL41_RS10235 2191498..2192331 + 834 WP_057024309.1 arylamine N-acetyltransferase -
FGL41_RS10240 2192457..2193209 + 753 WP_057024310.1 outer membrane beta-barrel protein -
FGL41_RS10245 2193270..2193584 - 315 WP_014718915.1 XRE family transcriptional regulator Antitoxin
FGL41_RS10250 2193574..2193924 - 351 WP_057024311.1 hypothetical protein Toxin
FGL41_RS10255 2194162..2195625 - 1464 WP_003192122.1 NADH-quinone oxidoreductase subunit NuoN -
FGL41_RS10260 2195633..2197165 - 1533 WP_057024312.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13758.68 Da        Isoelectric Point: 9.7334

>T288492 WP_057024311.1 NZ_LR590482:c2193924-2193574 [Pseudomonas synxantha]
MDALFIELPAFERHRKDYLSDELFQGFQQELMKTPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLTPHHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11755.58 Da        Isoelectric Point: 10.6525

>AT288492 WP_014718915.1 NZ_LR590482:c2193584-2193270 [Pseudomonas synxantha]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0R2YXS2

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0N117

References