Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 1062523..1063120 Replicon chromosome
Accession NZ_LR535679
Organism Campylobacter showae isolate B91_SC

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag E4V70_RS05275 Protein ID WP_197730461.1
Coordinates 1062797..1063120 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag E4V70_RS05270 Protein ID WP_103641294.1
Coordinates 1062523..1062804 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4V70_RS05255 1058324..1059784 + 1461 WP_122863391.1 aldehyde dehydrogenase family protein -
E4V70_RS10720 1059830..1059982 - 153 WP_163026479.1 hypothetical protein -
E4V70_RS05260 1060025..1060864 - 840 WP_122863390.1 DUF364 domain-containing protein -
E4V70_RS05265 1061321..1062439 + 1119 WP_122863389.1 tyrosine-type recombinase/integrase -
E4V70_RS05270 1062523..1062804 - 282 WP_103641294.1 helix-turn-helix domain-containing protein Antitoxin
E4V70_RS05275 1062797..1063120 - 324 WP_197730461.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E4V70_RS05280 1063541..1063771 + 231 WP_122863388.1 hypothetical protein -
E4V70_RS05285 1063802..1065427 + 1626 WP_134482483.1 hypothetical protein -
E4V70_RS10725 1065754..1065921 + 168 WP_163026478.1 hypothetical protein -
E4V70_RS05290 1065931..1066668 + 738 WP_122863386.1 disulfide bond formation protein B -
E4V70_RS05295 1066677..1067564 + 888 WP_122863385.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-85)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12264.40 Da        Isoelectric Point: 10.2170

>T288372 WP_197730461.1 NZ_LR535679:c1063120-1062797 [Campylobacter showae]
MWEITFLDDRVAEEFKALPPKISANMTHIFKLLRLYGNQVGEPQTKSLGDGLFEIRAKGAEGIGRGIFCYMTGRRIYILH
VFVKKGDRIPQKELDIAKNRLKELKNA

Download         Length: 324 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10695.40 Da        Isoelectric Point: 6.3657

>AT288372 WP_103641294.1 NZ_LR535679:c1062804-1062523 [Campylobacter showae]
MPEVKFDDVFNEMMKNDEFRAEYEALMPEYELKSELIKARIKSGLTQSQLAERMGMKQSNLARLESASGDFKFQTIIKYA
KALGLKQLNIALN

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References