287946

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 352709..353367 Replicon chromosome
Accession NZ_LR134490
Organism Haemophilus influenzae strain NCTC11873

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EL230_RS01795 Protein ID WP_126513432.1
Coordinates 352709..353056 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EL230_RS01800 Protein ID WP_126513433.1
Coordinates 353053..353367 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL230_RS01770 348540..348911 + 372 WP_126513427.1 hypothetical protein -
EL230_RS01775 348901..349104 + 204 WP_126513428.1 hypothetical protein -
EL230_RS01780 349091..349612 + 522 WP_126513429.1 hypothetical protein -
EL230_RS01785 349605..349997 + 393 WP_126513430.1 hypothetical protein -
EL230_RS01790 349985..352177 + 2193 WP_126513431.1 DUF927 domain-containing protein -
EL230_RS01795 352709..353056 + 348 WP_126513432.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL230_RS01800 353053..353367 + 315 WP_126513433.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EL230_RS01805 353508..354596 + 1089 WP_105876175.1 ATP-binding protein -
EL230_RS01810 354897..357482 - 2586 WP_126513434.1 DNA mismatch repair protein MutS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(16-112)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-82)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13393.27 Da        Isoelectric Point: 9.6118

>T287946 WP_126513432.1 NZ_LR134490:352709-353056 [Haemophilus influenzae]
MKLAFVELPFFEKYRAEYLSDDEYRALQNELLENPEKGDLIQGSNGLRKIRVANSKRNKGKRGGARAIYYYYINNQTIYF
FTIYGKETKDDLKPEELKVLAQLANSIKKITGETQ

Download         Length: 348 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11918.89 Da        Isoelectric Point: 10.8579

>AT287946 WP_126513433.1 NZ_LR134490:353053-353367 [Haemophilus influenzae]
MTKRNLFEELKQGFEEMGRHLEGKITLRTETLEKPSPITITPEEVKAIRQRLNLSQAVFARKLRTSVRTFQAWEQGKTKP
SAHASLLLRMVDKAPQTFELIAGI

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References