Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4441966..4442636 Replicon chromosome
Accession NZ_LR134485
Organism Citrobacter youngae strain NCTC13709

Toxin (Protein)


Gene name higB Uniprot ID A0A6N6JXY6
Locus tag EL296_RS22005 Protein ID WP_046671374.1
Coordinates 4442334..4442636 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EL296_RS22000 Protein ID WP_048213890.1
Coordinates 4441966..4442307 (-) Length 114 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(9-98)

Antitoxin

(18-69)


Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11819.43 Da        Isoelectric Point: 9.9581

>T287940 WP_046671374.1 NZ_LR134485:c4442636-4442334 [Citrobacter youngae]
MSKSLNIRSFRDTWLEDFFERATSHRKIPADIHTALARKLDIINAAVSHRDLRSPPGNRYEELTGKLQEYSSIRVNKQYR
LIFKWVNGKAEDVYLDPHIY

Download         Length: 303 bp


Antitoxin


Download         Length: 114 a.a.        Molecular weight: 13089.90 Da        Isoelectric Point: 6.4763

>AT287940 WP_048213890.1 NZ_LR134485:c4442307-4441966 [Citrobacter youngae]
MKQATRKPTTVGDILQYEYLEPLELKINDLAEILHVHRNTVSALVNNNRKLTTDMAFRLAKAFDTSVDFWRNLQAAVDLW
EVENDMRAQEELNRIVSVKDFIAQRNSESKKVA

Download         Length: 342 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6N6JXY6


Antitoxin

Source ID Structure

References