287789

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2320832..2321016 Replicon chromosome
Accession NZ_LR134351
Organism Staphylococcus aureus strain NCTC13811

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EL160_RS12420 Protein ID WP_000482647.1
Coordinates 2320909..2321016 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2320832..2320892 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL160_RS12395 2316342..2316509 - 168 Protein_2304 hypothetical protein -
EL160_RS12405 2316740..2318473 - 1734 WP_129545282.1 ABC transporter ATP-binding protein/permease -
EL160_RS12410 2318498..2320261 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2320832..2320892 + 61 - - Antitoxin
EL160_RS12420 2320909..2321016 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EL160_RS12425 2321150..2321536 - 387 WP_000779351.1 flippase GtxA -
EL160_RS12430 2321804..2322946 + 1143 WP_001176855.1 glycerate kinase -
EL160_RS12435 2323006..2323665 + 660 WP_000831298.1 membrane protein -
EL160_RS12440 2323847..2325058 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
EL160_RS12445 2325181..2325654 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T287789 WP_000482647.1 NZ_LR134351:c2321016-2320909 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT287789 NZ_LR134351:2320832-2320892 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References