287786

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2032342..2032558 Replicon chromosome
Accession NZ_LR134351
Organism Staphylococcus aureus strain NCTC13811

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag EL160_RS10850 Protein ID WP_073392962.1
Coordinates 2032454..2032558 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2032342..2032397 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL160_RS10830 2027435..2027755 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EL160_RS10835 2027757..2028737 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
EL160_RS10840 2029003..2030094 + 1092 WP_000495684.1 hypothetical protein -
EL160_RS10845 2030382..2032028 + 1647 WP_042363653.1 IS1182-like element ISSau3 family transposase -
- 2032342..2032397 + 56 - - Antitoxin
EL160_RS10850 2032454..2032558 - 105 WP_073392962.1 hypothetical protein Toxin
EL160_RS10860 2033238..2033396 + 159 WP_001792784.1 hypothetical protein -
EL160_RS10870 2034055..2034912 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
EL160_RS10875 2034980..2035762 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2030382..2032028 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T287786 WP_073392962.1 NZ_LR134351:c2032558-2032454 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp


Antitoxin


Download         Length: 56 bp

>AT287786 NZ_LR134351:2032342-2032397 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References