Detailed information of TA system TA287785

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-SprA2AS/-
• Location: 2032296..2032558
• Replicon: chromosome
• Accession: NZ_LR134351
• Organism: Staphylococcus aureus strain NCTC13811

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: EL160_RS10850
• Protein ID: WP_073392962.1
• Coordinates: 2032454..2032558 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2032296..2032459 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL160_RS10830	2027435..2027755	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
EL160_RS10835	2027757..2028737	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
EL160_RS10840	2029003..2030094	+	1092	WP_000495684.1	hypothetical protein	-
EL160_RS10845	2030382..2032028	+	1647	WP_042363653.1	IS1182-like element ISSau3 family transposase	-
-	2032296..2032459	+	164	-	-	Antitoxin
EL160_RS10850	2032454..2032558	-	105	WP_073392962.1	hypothetical protein	Toxin
EL160_RS10860	2033238..2033396	+	159	WP_001792784.1	hypothetical protein	-
EL160_RS10870	2034055..2034912	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
EL160_RS10875	2034980..2035762	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2030382..2032028	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T287785 WP_073392962.1 NZ_LR134351:c2032558-2032454 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 164 bp

>AT287785 NZ_LR134351:2032296-2032459 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Structures

Antitoxin